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What are Peripheral Nerve Tumors?

Peripheral nerve tumors are growths in or near the strands of nerves that transmit signals from your brain to the rest of your body. They can occur anywhere in the body and most often are not cancerous (malignant) although they can cause discomfort, nerve damage, and loss of function in the affected area.

What are the Causes of Peripheral Nerve Tumors?

The exact causes of peripheral nerve tumors are unknown. Some of them are associated with inherited diseases like neurofibromatosis (types 1 and 2) and schwannomatosis. Others are brought on by a faulty gene or triggered by an injury or surgery.

What are the Symptoms of Peripheral Nerve Tumors?

Signs and symptoms of peripheral nerve tumors include:

  • Swelling
  • Lump under your skin
  • Pain, tingling, or numbness
  • Weakness or loss of function in the affected area
  • Dizziness 

Diagnosis of Peripheral Nerve Tumors

Your doctor will review your medical history and symptoms and based on this a physical and neurological examination will be performed. Your doctor may also recommend the following diagnostic tests:

  • Magnetic Resonance Imaging: The MRI study uses a magnetic field and radio waves to produce detailed images of the area affected by nerve damage.
  • Electromyography (EMG): A thin-needle electrode inserted into your muscle records the electrical activity of your muscle at rest and in motion in an EMG. Nerve damage can be indicated by decreased muscular activation.
  • Nerve Conduction Study: During this study, the electrical signals that flow through your nerves are measured using electrodes inserted at two separate places on your body.
  • Computerized Tomography (CT) Scan: This is an imaging technique that uses special x-rays to obtain cross-sectional images of the internal structures of the body. A contrast material or dye may be administered intravenously to obtain a more detailed view.
  • Tumor Biopsy: If imaging tests reveal a nerve tumor, your doctor may take a small sample of cells (biopsy) from the tumor for laboratory analysis. You may require local or general anesthesia for the biopsy, depending on the size and location of the tumor. 

What are the Treatments for Peripheral Nerve Tumors?

Treatment options for peripheral nerve tumors include:

  • Regular Monitoring: If the tumor is in a location that makes removal problematic or if the tumor is small, slow-growing, and causes few or no signs and symptoms, monitoring its growth may be an option. Regular examinations are required, and you may be subjected to CT or MRI scans every few months to determine whether your tumor is developing.
  • Surgery: A peripheral nerve tumor may require surgery if it is malignant. The goal of surgery is to remove the entire tumor while preserving healthy tissue and nerves in the surrounding area. When this isn't an option, doctors will remove as much of the tumor as feasible and use radiation therapy or chemotherapy to destroy the non-resectable parts of the tumor. Microsurgery's high-powered microscopes make it easier to identify a tumor from healthy tissue. During surgery, doctors can also check the function of nerves, which helps to retain healthy tissue.
  • Stereotactic Radiosurgery: Your doctor may recommend stereotactic radiosurgery to treat some peripheral nerve tumors in or around the brain.  Stereotactic radiosurgery options, such as gamma knife radiosurgery can administer radiation to a tumor accurately without the doctor having to make an incision.
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